Run for 21


In honor of the third copy of the twenty-first chromosome, the Down Syndrome Association of Greater St. Louis invites you to run a 5k (plus a little extra!). The Run for 21 (formerly Relay and Run for 21) celebrates the amazing lives of people with Down syndrome. The race coincides with our largest celebration of the year – Step Up for Down Syndrome. All proceeds will benefit the Down Syndrome Association of Greater St. Louis and DADS Community Outreach Fund

The event includes a 3.21 mile certified race through beautiful forest park and ends at the DSAGSL’s largest celebration of the year Step Up for Down Syndrome (SUDS). Race amenities include a race shirt, finisher medal, and one wrist band for entry into SUDS. We encourage runners to start a SUDS Team and raise additional funds beyond their race registration to earn more wristbands and SUDS t-shirts for family and friends.  

Relay and Run for 21 was started by the amazing Marvin Family nine years ago. Thank you so much to the Marvin Family and Dads Appreciating Down Syndrome (DADS St. Louis) for their tireless efforts to make the Relay and Run for 21 an amazing event. The DSAGSL is honored to host this run and continue to see it raise awareness for Down syndrome

2020 Run for 21 5k Race | June 7, 2020

Registration starts at 7am | Race starts at 8am

2020 Course Map

The Run for 21 race starts and ends in the Upper Muny Parking Lot in beautiful Forest Park and culminates in the DSAGSL’s the largest celebration of th year – Step Up for Down Syndrome.

The route for this 3.21 mile race is a loop course with two short out-and-back legs. Registration and timing by Fleet Feet St. Louis.

More Information


3/4/2020 – 3/21/2020: $25
3/22/2019 – 4/30/2020 $30
5/1/2020 – 6/6/2020: $35
6/7/2020 (Day of Event): $40

Packet Pick Up Times

6/6/2020 DSAGSL Office from 1pm-5pm

6/7/2020 Upper Muny Parking Lot from 7am-8am


Awards will be presented to the top 3 in the male and female age groups: 
12 and under, 13-19, 20-29, 30-39, 40-49, 50-59, 60-69, 70 and over.

Dogs and Strollers*
Dogs that are on leashes and strollers are allowed. We just request that you lineup at the back of the start so as not to impede the runners. 
Out of respect for our individuals with Down Syndrome who have a fear of dogs we ask that you do not bring your furry friends into the Step Up for Down Syndrome Celebration following the race. Thank you for understanding!

Sponsorship Opportunities

The Run for 21 race starts and ends at the DSAGSL’s the largest celebration of th year – Step Up for Down Syndrome which hosts more than 2,500 people.  It’s a great opportunity to showcase your business’ committment to supporting the Down syndrome community.

Complete the sponsorship form and return to Director of Special Events, Amber McWIlliams. or 8531 Page Ave, Suite 120. St. Louis, MO 63114.