Run for 21


Sunday, June 5, 2022

7:00-7:45am | Day Of Registration & Race Packet Pickup

8:00am | Shotgun Start

After Race-9:30am | All You Can Eat Pancake Breakfast 

9:00am-12:30pm | Step Up Celebration

In honor of the third copy of the twenty-first chromosome, we invite you to run our 5k (plus a little extra) with us on June 5th in beautiful Forest Park!  Can’t make it in person? No worries! There is a virtual 5k option, as well. This 3.21 mile race will take place right before our largest event of the year, Step Up for Down Syndrome begins.  We encourage you to start a Step Up team and enjoy the celebration after the race! Visit our Step Up for Down Syndrome page for more information.  

Race amenities include a race shirt, finisher medal, and personalized bib. 

Do Something Extra and Register Today!

Pricing, Awards, & Race Packet Pick Up


1/17 – 3/21: $30

3/22 – 4/30 $35

5/1 – 6/5: $40

Deadline to register: 6/1

Packet Pick Up Times

6/2 DSAGSL Office 9am-4pm

6/3 DSAGSL Office 9am-4pm

6/4 DSAGSL Office 1-5pm

6/5 Race Day 7-7:45am


Awards are presented to top 3 in the male & female age groups: 
12 & under, 13-19, 20-29, 30-39, 40-49, 50-59, 60-69, 70 & over.

Dogs and Strollers

Dogs that are on leashes and strollers are allowed. We just request that you lineup at the back of the start so as not to impede the runners. 
Out of respect for our individuals with Down Syndrome who have a fear of dogs we ask that you do not bring your furry friends into the Step Up for Down Syndrome Celebration following the race. Thank you for understanding!

Race Course & Timing

DSAGSL works with Fleet Feet for bibs and timing.  More information about race course coming soon!

History of Run for 21

The Run for 21 (formerly Relay and Run for 21) celebrates the amazing lives of people with Down syndrome. The race coincides with our largest celebration of the year – Step Up for Down Syndrome. This year, due to unique circumstances, we will be doing everything virtually. All proceeds will benefit the Down Syndrome Association of Greater St. Louis and DADS Community Outreach Fund. 

Relay and Run for 21 was started by the amazing Marvin Family nine years ago. Thank you so much to the Marvin Family and Dads Appreciating Down Syndrome (DADS St. Louis) for their tireless efforts to make the Relay and Run for 21 an amazing event. The DSAGSL is honored to host this run and continue to see it raise awareness for Down syndrome

Sponsorship Opportunities

The Run for 21 virtual race has several great sponsorship opportunities.  Outreach will be not only to participants of the Run for 21 event, but also to all those attending Step Up for Down Syndrome virtual event.

Please contact Director of Special Events, Emily Fisher, for more information. or 314-961-2504

Thank You 2022 Sponsors!